New anti-viral composition effective in combating influenza A viruses


Scientists have developed a unique anti-viral composition that can effectively provide protection against several influenza A viruses such as H1N1, H3N2, H5N1 and H7N9.

Influenza, a contagious respiratory illness that infects the nose, throat and lungs, is among the leading causes of death, according to the Centres for Disease Control and Prevention.

The new anti-viral composition is made up of three siRNAs (small interfering ribonucleic acids) targeted at three genes and encapsulated in hybrid polyelectrolyte microcapsules, the Sputnik reported.

The results will be used to develop a drug to prevent and treat the viral infection, according to Alexander Timin from the Tomsk Polytechnic University in Russia.

The team developed 11 new siRNAs with anti-viral activity in vitro that can suppress conserved and consensus sequences in the genome of the influenza A virus on the NS, PA and NP genes.

Anti-viral properties were screened and three siRNAs -- PA-1630, NP-717 and NS-777 -- were selected for their most pronounced inhibitory ability, the report said. Read More

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