Heena Sharma Blog

Turns out, a high cholesterol diet can trigger changes in the immune system that can lead to a serious form of fatty liver disease . Known as non-alcoholic steatohepatitis (NASH), it eventually progresses to cirrhosis or liver cancer, especially in those with obesity or Type 2 diabetes . Researchers at Keck School of Medicine found how a toxic combination of dietary fat and cholesterol impacts the behaviour of macrophages, a type of white blood cell, in the liver. The findings of the study are published in the Journal of Hepatology. Using a mouse model, the study detailed the cascade of events in the immune system that eventually leads to the type of liver inflammation and scarring that is commonly seen in patients with NASH. "Despite its increasing prevalence and burden to the health care system, there are currently no food and drug administration-approved therapies for non-alcoholic fatty liver disease," said Hugo Rosen, study's corresponding author

Consuming a higher amount of green leafy vegetables can help reduce the risk of developing liver disease , a new study has suggested. Liver steatosis or fatty liver is a common disease that affects approximately 25 per cent of the global population. The most important causes are overweight or high alcohol consumption and there is currently no medical treatment for the disease. In a study published in the journal PNAS, researchers from Karolinska Institute showed how a larger intake of inorganic nitrate, which occurs naturally in many types of vegetable, reduces accumulation of fat in the liver. They also showed how a greater intake of inorganic nitrate can prevent the accumulation of fat in the liver. "When we supplemented with dietary nitrate to mice fed with a high-fat and sugar Western diet, we noticed a significantly lower proportion of fat in the liver," said Mattias Carlstrom, a researcher. Read More Business Standard