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Showing posts with the label NEUROSTEROIDS

Here's yet another reason to avoid high-fat food

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Turns out, a high cholesterol diet can trigger changes in the immune system that can lead to a serious form of fatty liver disease . Known as non-alcoholic steatohepatitis (NASH), it eventually progresses to cirrhosis or liver cancer, especially in those with obesity or Type 2 diabetes . Researchers at Keck School of Medicine found how a toxic combination of dietary fat and cholesterol impacts the behaviour of macrophages, a type of white blood cell, in the liver. The findings of the study are published in the Journal of Hepatology. Using a mouse model, the study detailed the cascade of events in the immune system that eventually leads to the type of liver inflammation and scarring that is commonly seen in patients with NASH. "Despite its increasing prevalence and burden to the health care system, there are currently no food and drug administration-approved therapies for non-alcoholic fatty liver disease," said Hugo Rosen, study's corresponding author

Adding cottonseed oil to your diet can lower cholesterol, finds study

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Cottonseed can drastically improve cholesterol profiles in young adult men, a recent study suggests. The researchers conducted a five-day outpatient feeding trial of 15 healthy, normal weight men to test the effects of diets enriched with cottonseed oil and olive oil on lipid profiles. The researchers found that a high-fat diet enriched with cottonseed oil drastically improved cholesterol profiles in young adult men. Participants showed significant reductions in cholesterol and triglycerides in the cottonseed oil trial compared to minimal changes on the olive oil-enriched diet . The results appear in the journal Nutrition Research. Jamie Cooper, the corresponding author of the study said, "One of the reasons these results were so surprising is because of the magnitude of change observed with the cottonseed oil diet. To see this amount of change in such a short period of time is exciting." The subjects, all healthy men between the ages of 18 and 45, were pr

Youth hormone necessary for conceiving after 40

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DHEA (dehydroepiandrosterone), also known as the youth hormone is an adrenal steroid hormone in the body synthesized by the adrenal glands, which are then converted into androgens, estrogen, and other hormones. These hormones are responsible to regulate fat and mineral metabolism, sexual and reproductive function, and energy levels. The level of DHEA increases until our body is in the late 20s, after which it starts declining with age. "DHEA supplements help by increasing the androgen levels within the ovarian environments to a normal range, which improves egg quality. The high-quality healthy eggs develop into high-quality embryos, which have a better chance of implantation and lower risks of miscarriage," said Dr. Sowjanya Aggarwal, Gynaecologist, Max Hospital, Vaishali. Read Complete Article